Prosthetic groups differ from co-enzymes in t | vedclass

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(B) Co-factors are non-protein constituents that are bound to the enzyme to make the enzyme catalytically active. They are classified into three types

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they (prosthetic groups) are tightly bound to apoenzymes.

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(B) Co-factors are non-protein constituents that are bound to the enzyme to make the enzyme catalytically active. They are classified into three types: prosthetic groups,co-enzymes,and metal ions. Prosthetic groups are organic compounds that are tightly bound to the apoenzyme (the protein portion of the enzyme). For example,in peroxidase and catalase,which catalyze the breakdown of hydrogen peroxide to water and oxygen,heme is the prosthetic group and it is a part of the active site of the enzyme. In contrast,co-enzymes are also organic compounds,but their association with the apoenzyme is only transient,usually occurring during the course of catalysis. Therefore,the fundamental difference is that prosthetic groups are tightly bound,whereas co-enzymes are loosely or transiently bound.

Prosthetic groups differ from co-enzymes in that

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